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Pawling Engineered Products

Engineered Elastomeric Technologies for Sealing, Clamping, Actuating

Life Sciences

Rubber Seals for the Life Science Market

At Pawling EP, we have developed specialty materials and processes designed especially for custom pharmaceutical and medical seals applications. From low bleed, FDA-compliant, and USP Class Vi certified materials (see CVI series) to unique inflatable seal designs, special cleaning procedures, and controlled (white room) manufacturing facilities, we are prepared to handle the unique sealing requirements of the industry. Application examples include:

  • Inflatable and compression seals for sterilizer doors and pharmaceutical washing machines
  • Inflatable seals for glove box isolators primarily used in aseptic manufacturing environments
  • Silicone septa used in pharmaceutical packaging or with gas and liquid chromatography equipment
  • Natural Rubber septa (our own formulation) for use with GC vials
  • Actuators to position and seal equipment trays during processing

Detailed Market Applications

Inflatable Sterilizer Door Seals
Sterlizer Doors SealsProduct: Pneuma-Seal
Use: Inflatable Seal
Description: Inflatable seals in durable fabric reinforced silicone or EPDM profiles are ideal for sealing vertical lift doors on floor mounted sterilizers, sliding doors on table top models, or large sliding doors on walk-in batch processing gas sterilizers. Rectangular Type 10X high pressure profiles are frequently chosen to minimize particle trapping pockets. (click image to view animation).
Inflatable Seals for Airtight Doors
Airtight Laboratory Door SealsProduct: Pneuma-Seal
Use: Inflatable Seal
Description: Airtight doors in virology laboratories, animal rooms and decontamination areas are tightly sealed with Pawling Engineered Products inflatable seals installed around the periphery of the door to expand radially outward. This design facilitates frequent access since there is no requirement to actuate multiple dogs, and there is no raised sill to obstruct personnel and equipment traffic (click image to view animation).
Inflatable Bathtub Seals
Inflatable Bathtub SealsProduct: Pneuma-Seal
Use: Inflatable Seal
Description: Sitdown bathtubs for the elderly or infirmed are made very "user friendly" by offering access and egress through hinged doors, hinged combination door and seat assemblies, or sliding doors. Once the bather is inside the tub, the door is closed and the inflatable seal automatically inflates to make a watertight seal as the tub fills (click image to view animation).
Vial Septa for Use in Gas Chromatography
GC Rubber SeptaProduct: Cepure
Use: Septa
Description: Gas chromatography is a method for separating substances in a mixture and measuring their relative quantities. A wide array of gas chromatography septa designs are readily available. Depending on the analysis, standard organic-based septa, such as Butyl or Natural Rubber, may be used; or Silicone septa may be required if the vial needs to be re-sealed or temperatures above 100°C are realized. GC septa consist of a rubber layer and either one or two fluoropolymer (PTFE, FEP, ETFE) layers which act as the main barrier. Because samples used in GC work can be volatile at room temperatures, it is important to choose the right GC septa for your application. Choosing the wrong septa could lead to compromised test results.
Injection Port Septa for GC
Injection Port SeptaProduct: Zero Injection Port Septa
Use: Injection Port Septa
Description: In gas chromatography, a liquid sample is injected into a gaseous system, maintained under elevated pressure (e.g. 20 psi) where it undergoes analysis in accordance with well known procedures. The equipment is provided with injection ports that are sealed by an elastomeric septum. Needles are utilized to penetrate the septum and to inject the sample into the injection port. For the injection port septum to work properly, it must be able to withstand high temperatures, be resistant to coring, and generate a low amount of bleed. All high performing injection port septa have the same characteristics. They are typically manufactured of silicone and molded to ensure proper fit, are conditioned for lower bleed even under high temperatures, and are designed to minimize coring (shedding of particles into the port liner). Regardless, volatile materials may be released when the septum is heated to temperature. Most chromatographs have a septum purge flow which is designed to "sweep" the volatiles away from the column; however, this does not entirely solve the problem. Efforts are underway to find the ultimate septum - one that contains zero contaminants and is long lasting. We believe our Zero injection port septum does the trick.
Vial Septa Used in Liquid Chromatography
HPLC Rubber SeptaProduct: Cepure
​Use: Septa
Description: High performance liquid chromatography (HPLC) is an analytical chromatographic technique used to separate ions or molecules dissolved in a solvent. Liquid Chromatography (LC), HPLC, and LC-MS require a slightly different septa design. Because the sample is less volatile, straight PTFE septa or pre-slit Silicone/PTFE septa designs may be used. A straight PTFE septum offers excellent solvent resistance and chemical compatibility, but does not re-seal upon puncturing. Pre-slit Silicone/PTFE septa prevent needle coring, offer moderate re-sealing, and provide for excellent sample-draw reproducibility. Use of non-pigmented silicones and PTFEs reduce the potential for contamination.
Vial Septa for Headspace Analysis
Headspace SeptaProduct: Cepure
Use: Septa
Description: Headspace Gas Chromatography is used to analyze both volatiles and semi-volatiles in gas, liquid and solid samples. Low extractable levels and excellent re-sealing characteristics are but two of the demands placed on Headspace Septa. For standard analyses or in the presence of ketones, straight Butyl or Butyl/PTFE septa may be used; however, if the vial needs to be re-sealed or is subjected to temperatures over 100° C, Silicone/PTFE septa are recommended.
Magnetic Compression Seal for Dental Sterilizers
Compression Seal for Dental SterilizersProduct: Custom Rubber and Plastic Products
Use: Compression Seal
Description: This sterilizer gasket withstands the rigors of high temperatures and latches the door by using magnets which are installed within the seal.  This dual system combines the seal and latch into one unit, which simplifies design.  Silicone is used to ensure the gasket maintains its effectiveness even under high temperatures.